Lynn B. Bailey, PhD

College of Family and Consumer Sciences

Foods and Nutrition

Department Head, Professor

Address:
280 Dawson Hall
305 Sanford Dr.
Athens, GA 30602

E-Mail:

workOffice Phone: 706-542-4256

Fax: 706-542-5059

Curriculum Vitae

Education

Degree Field of Study Institution Graduation
PhD Nutrition Purdue University 1975
MS Nutrition Clemson University 1972
BS Biology Winthrop University 1970

Research

Folate status and metabolism, maternal health, fetal development.

The Folate Research Group conducts clinical research in women of reproductive age to assess the metabolic and epigenetic response to changes in folate intake. The primary objective of the folate-related research studies is to provide research evidence on which revised folate-related public health recommendations can be based. The long-range goal of the Folate Research Program is to optimize maternal health and fetal development and growth.

Areas of Expertise

My area of expertise is the assessment of folate status biomarkers of population sub-groups and related data interpretation in diverse research and clinical settings and as a basis for  public health policy decisions including  folate intake recommendations and interventions including  supplementation and fortification.

Current Scholarly Endeavors Related to Areas of Expertise

  • International Micronutrient Forum Technical Consultation Co-Chair “Folate status in women and neural tube defects risk-reduction”
  • Pregnancy to Infancy (P2i) Center of Excellence on Preconception Care Advisory Committee; UGA-The Forum Institute Partnership

Prior Professional Positions

Organization / Department Title Years of Service
University of Georgia Professor and Department Head August 1, 2011- present
University of Florida Professor, Food Science & Human Nutrition 1987-2011
University of Florida Associate Professor, Food Science & Human Nutrition 1982-1987
University of Florida Assistant Professor 1977-1981
Purdue University Post-Doctoral Research Associate, Lecturer, Food & Nutrition Department 1975-1977

Awards

Award Name Awarded By Year Awarded
Purdue University Hall of Fame Foods and Nutrition Department Purdue University 2011
University of Florida Teacher/Scholar of the Year University of Florida 2008-2009
Centrum Science Award for Research Accomplishments in Human Nutrition American Society for Nutrition 2004
Outstanding Professional Skill Award for the Distance Education (team award) International Association for Communication 2004
Agnes Higgins Award for Accomplishments in Fetal and Maternal Medicine March of Dimes 2000-2001
Gold Image Award (team award) UF/IFAS 2003
Blue Key Distinguished Faculty Award Blue Key 2002
Research Foundation Professorship University of Florida 2001
Senior Research Scientist Award Gamma Sigma Delta- Florida Chapter 2001
International Research Scientist Award Nominee Gamma Sigma Delta- Florida Chapter 2001
Volunteer of the Year March of Dimes- North Central Florida 2001
Professional Merit Award University of Florida 1999
Professional Excellence Award University of Florida 1997-1998
National Award for Superior Service in Research USDA 1996
Outstanding Teaching Award University of Florida 1995-1996
Distinguished Alumni Winthrop University 1995
Award (Readex) Most Outstanding Published Article American Dietetic Association 1995
Centennial Distinguished Alumni Clemson University 1988

Journal Articles

Selected (2008-Present)

Jorge Rosenthal, Natalia Largaespada, Lynn Bailey, Michael Cannon, CJ Alverson, Dayrin Ortiz, Gail Kauwell, Joe Sniezek, Ramon Figueroa, Robyn Daly, and Peter Allen. Folate concentration and its association with vitamin B12 status among non-pregnant women of childbearing age.  Belize National Micronutrient Survey. Journal of Nutrition (under review).

Anna K. Knight, et al., Hea Jin Park, Lynn B. Bailey, and Alicia K. Smith. An epigenetic clock for gestational age at birth based on blood methylation data. Genome Biology 7:206, doi: 10.1186/s13059-016-1068-z, 2016.

Gordon, J. D., Hausman, D. B., Bailey, L. B., Lewis, R. D., Laing, E. M., & Park, H. J. Impact of gluten-containing foods on folate intake of women of childbearing age. The Digest, 51(1), 2-7, 2016

Cheng T-Y C, Makar, K W, Neuhouser M L, Miller JW, Song X, Brown EC, Beresford, Zheng Y, Poole EM, Galbraith RL, Duggan DJ, Habermann N, Bailey LB, Maneval DR, Caueill MA, Toriola, AT, Green R, Ulrich CM. Folate mediated one-carbon metabolism genes and interactions with nutritional factors on colorectal cancer risk: Women’s Health Initiative Observational Study. Cancer, doi: 10.1002/cncr.29465, 2015

Bailey, LB, Stover P, McNulty, H, Fenech M, Gregory, JF, Mills J, Pfeiffer C, Fazili Z, Zhang, M, Ueland PM, Molloy A, Caudill, M, Shane, B, Berry RJ, Bailey R, Hausman D, Raghavan R, Raiten, D. Biomarkers of Nutrition for Development-Folate Review. Journal of Nutrition, 145: 1635S, 2015.

Bae J, Ulrich C, Neuhouser M, Malysheva O, Bailey L, Xiao L, Brown E, Cushing-H K, Zheng Y, Cheng T-Y, Miller J, Green R, Lane D, Beresford S, Caudill M. Plasma choline metabolites and colorectal can risk in Women’s Health Initiative Observational Study. Cancer Research, Oct 21, 2014.

Abbenhardt C, Miller J, Song X, Brown E, Cheng D, Wener M, Zheng Y, Toriola AT, Neuhouser, ML, Beresford S, Makar K, Bailey L, Maneval DR, Green R, Manson JE, van Horn L, Ulrich CM. Relationship between biomarkers of one-carbon metabolism and biomarkers of inflammation. J Nutrition, 144: 714, 2014.

Bae S, Ulrich CM, Bailey LB, Malysheva O, Brown EC, Neuhouser L, Cheng D, Miller JW, Zheng Y, Xiao L, Hou L, Song X, Buck K, Beresford, Caudill, M. Impact of folic acid fortification on global DNA methylation on one-carbon biomarkers in the Women’s Health Initiative Observational Study cohort. Epigenetics, March 9; 396, 2014.

da Silva VR, Hausman DB, Kauwell GP, Sokolow A, Tackett RL, Rathbun SL, Bailey, LB. Obesity affects short-term folate pharmacokinetics in women of childbearing age. Int J Obesity, April doi:10.1038/ijo.2013.41: 1-3, 2013.

Quinlivan EP, Crider KS, Zhu J-H, Maneval DR, Hao L, Li Zhu, Rasmussen SA, Berry RJ, Bailey, LB. Hypomethylation of serum blood clot DNA, but not plasma EDTA-blood cell pellet DNA, from vitamin B12-deficient subjects. PLoS ONE 8(6): e65241. Doi:10.1371/journal.pone.0065241, 2013.

Tinker, S, Hamner HC, Berry RJ, Bailey, LB, Pfeiffer CM. Does obesity modify the association of supplemental folic acid with folate status among women of childbearing age in the United States? Birth Defects Research Part A: Clinical and Molecular Teratology 94: 749-755, 2012.

Quanhe Y; Bailey LB; Clarke R; Flanders WD; Liu T; Yesupriya A; Khoury M; Friedman JM. Prospective Study of Methylenetetrahydrofolate Reductase (MTHFR) Variant C677T and Risk for All-Cause and Cardiovascular Mortality among 6000 U.S. Adults. Am J Clin Nutr 95:1-10, 2012.

Crider KS, Bailey LB. Folate’s role in DNA methylation. Advances in Nutrition 3: 21-38, 2012.

Crider KS, Quinlivan EP, Berry RJ, Hao L, Li Z, Maneval D, Yang TP, Rasmussen SA, Yang Q, Zhu J-H, Hu DJ, Bailey, LB. Genomic DNA methylation changes in response to folic acid supplementation in a population-based intervention study among women of reproductive age. PLoS ONE 6(12): e28144.doi:10.1371/journal.pone.0028144, 2011.

Wilson S, Courchene B, Russel K, Bailey L. Oral contraceptive use: impact on folate, vitamin B6, and vitamin B12 status. Nut Rev 69: 572-583, 2011.

Crider KS, Bailey, LB, Berry RJ. Folic acid food fortification-Its History, Impact, Concern, and Future Direction. Nutrients do1:10.33390/nu30x000x, 2011.

Crider K, Bailey LB. Defying birth defects through diet. Genome Medicine 3:9, 2011.

Crida K, Zhu J-H, Ling H, Yang Q-H, Yang T, Gindler, J, Maneval DR, Quinlivan EP, Li Z, Bailey LB, Berry RJ. Methylenetetrahydrofolate reductase 677C→T genotype is associated with folate and homocysteine concentration in a large population-based double-blind trial of folic acid supplementation. Am J Clin Nutr 93: 1365, 2011.

Yeung LF, Cogswell ME, Carriquiry A, Bailey LB, Pfeiffer CM, Berry RJ. Contributions of enriched cereal grain products, ready-to-eat cereal, and supplements to the folic acid and vitamin B12 status in US children: National Health and Nutrition Examination Survey (NHANES) 2003-2006. Am J Clin Nutr 93:1-14, 2010.

Yang Q, Cogswell, ME, Hamner H, Carriquiry A, Bailey LB, Pfeiffer CM, Berry RJ. Folic acid source, usual intake, and folate and vitamin B12 status in US adults: National Health and Nutrition Examination Survey, 2003-2006. Am J Clin Nutr 91:64-72, 2010.

Von Castel-Roberts, K, Whitman AR, Maneval DR, Bailey, LB, Kauwell GPA. Contribution of seafood to total vitamin B12 intake and status of young adult men and women. J Aquatic Food Product Technology 19:26-37, 2010

Hardlei TF, Moerkbak AL, Bor MV, Bailey LB, Hvas A-M, Nexo E. Assessment of vitamin B12 absorption based on the accumulation of orally administered cyanocobalamin on transcobalamin.Clinical Chemistry 56: 432-36, 2010.

Pietrzik, K, Bailey, LB., Shane B. Folic acid and L-5-methyltetrahydrofolate: Comparison of Clinical Pharmacokinetics and Pharmacodynamics. Clinical Pharmacokinetics 49: 535-48, 2010.

Bor M-V, von Castel-Roberts K M ,Kauwell, GPA,Stabler SP,Allen RH ,Maneval DR ,Bailey LB, and Nexo E.Daily intake of 4 to 7 micrograms of dietary vitamin B12 is associated with steady levels of vitamin B12-related biomarkers in a healthy young population, Am J Clin Nutr 91: 571-7, 2010.

Simpson JL, Bailey, LB, Shane B, Holzgreve W, Pietrzik K. Micronutrients and women of reproductive potential:required dietary intake and consequences of dietary deficiency or excess.Part I-Folates, Vitamin B12, Vitamin B6.J Maternal-Fetal and Neonatal Medicine.23: 1323-43, 2010.

Simpson JL, Bailey, LB, Shane B, Holzgreve W, Pietrzik K. Micronutrients and women of reproductive potential:required dietary intake and consequences of dietary deficiency or excess. Part II- Vitamin D, Vitamin A, Iron, Zinc, Iodine, Essential Fatty Acids. J Maternal-Fetal and Neonatal Medicine. DOI: 10.3109/14767051003678226. Early Online 1-24, 2010.

Jiang Hui Zhu, Dale J. Hu, Ling Hao, Bao Lan Zhang, Mary E. Cogswell, Lynn B. Bailey, Zhu Li and R.J. Berry. Iron, folate, and B12 deficiencies and their associations with anemia among women of childbearing age in a rural area in northern China. Int J Vit Nut Res 80: 144-54, 2010.

Zhu J-H, Hao L, Li S, Bailey LB, Zhu, Li. MTHFR TGFB3, and TBFA polymorphisms and their association with the risk of non-syndromic cleft lip and cleft palate in China. Am J Medical Genetics Part A 9999:1-9, 2009.

Ling H, Yang Q-H, Li Z, Bailey LB, Zhu J-H, Hu DJ, Zhang L, Erickson JD, Zhang L, Gindler J, Li S, Berry RJ. Folate status and homocysteine response to folic acid doses and withdrawal among young Chinese women in a large-scale randomized double blind trial. Am J Clin Nutr 88: 448-57, 2008.

Editorial Appointments

Position Name of Journal Year(s)
Editorial Board Nutrition Reviews 1997-2000
Editorial Board Journal of Nutrition 1991-1995
Associate Editor Journal of Nutrition 1989-1990

Service

Organization Title Year(s) Service Type
Micronutrient Forum Co-chair 2016- present Providing leadership to international group of scientists charged with developing a “roadmap” to reduce neural tube defects globally
UGA/The Forum Institute Advisory Board Member 2016- present Providing guidance regarding development of a new Preconception to Infancy (P2i) Center for Excellence on Preconception Care
National Institutes of Health, National Institute of Maternal and Child Health Chair Biomarkers of Nutrition for Development Folate Panel 2011- present
Centers of Disease Control and Prevention Scientific Advisor 2004-2011 Provided scientific advice for global folate status assessment and folic acid intervention studies conducted in China, Honduras, Guatemala, and Belize.
United States Department of Agriculture National Research Initiatives Competitive Grant Program Grant Reviewer 1991-2007 (Panel Member and Ad-Hoc)
National Academy of Sciences Scientific Expert 2004-2005 Provided scientific advice, presented, and wrote report for reformulation of nutrients in meals for combat soldiers exposed to extreme physical stress.
National Academy of Sciences, Institute of Medicine Committee on Examination of Evolving Science for Dietary Supplements 2001-2002 Provided scientific advice, presented and wrote review related to health benefits of dietary supplements.
American Society for Nutritional Sciences Nominating Committee and Chair for Centrum Award in Human Nutrition 2000-2002
Pan American Health Organization and the University of Chile, Santiago, Chile Expert Advisor and Research Collaborator 1998-2002 Provided scientific advice and analyzed fortified bread for “Chilean Folic Acid Intervention Program and Evaluation to Reduce Neural Tube Defects”.
National Institutes of Health Program Grant Reviewer 2000 Reviewed research productivity and conducted site visit for multi-center research program to investigate the etiology of folate-related birth defects
March of Dimes- International Division National Advisory Group on Research Objectives 1999 Derived global research objectives for the optimization of fetal development and growth.
National Academy of Sciences Institute of Medicine Committee, Chair Folate Panel 1996-1998 Reviewed scientific literature and chaired committee efforts to derive the folate-related recommendations for Dietary Reference Intakes for “Folate and Other B Vitamins”.
National Institutes of Health Office of Dietary Supplements, Advisory Panel 1996 Provided scientific advice regarding the nutritional benefit of dietary supplements.
National Institutes of Health Member of Scientific Reviewer Panel for Optimal Calcium Intake Consensus Conference 1994
American Society of Nutritional Sciences National Treasurer and Chair of Budget and Finance Committee 1993
US Congress Congressional Witness 1993 Presented testimony on “Regulation of Dietary Supplements as Food”
National Academy of Sciences Scientific Adviosr 1993 Scientific advisor to determine if data sufficient to derive new Recommended Dietary Allowances
Food and Drug Administration Folic Acid Food Advisory Committee member 1992-1994 Recommended fortification of US food supply with folic acid culminating in 1996 FDA-mandated fortification of all “enriched” cereal grains products with folic acid.
Institute of Food Technology Food Policy Committee 1992
American Society of Nutritional Sciences Executive Committee 1991-1995
American Dietetic Association, Council on Research Chair Research Awards Committee 1991-1992
American Society of Nutritional Sciences Lederle Award Committee 1991
Gamma Sigma Delta President Florida Division 1991
Food and Drug Administration Scientific Advisor 1991 Reviewed scientific evidence and coauthored report: “Folate and Neural Tube Defects”.
National Aeronautics and Space Administration Committee for Nutrient Requirements for Astronauts 1991 Derived nutrient requirements for astronauts that were published in the “Nutritional Requirements for Space Station Astronauts”.
Institute of Food Technologists Babcock-Hart Awards Committee 1990-1991
American Dietetic Association Council on Research 1989-1992 Reviewed and selected research grant award recipients.
Centers for Disease Control Expert Scientific Committee 1989-1991 Scientific advisor for proposed folic acid birth defect intervention trial conducted in China
American Society of Nutritional Sciences Expert Scientific Committee 1989 Evaluated data to address assessing status of hard-to reach population groups.
Institute of Food Technology Nominating Committee 1989
American Society Nutritional Sciences Nominating Committee 1988, 2001-2003
Institute of Food Technology National Chair Nutrition Division 1987 Directed activities of national Nutrition Division, planned national Nutrition Division meeting, planned symposium that took place at national meeting.
National Institutes of Health National Cancer Institute 1987 Evaluation research programs for large-scale multi-center grant. Site visitor to university research program facilities.
Institute of Food Technology Director of the “National Food and Nutrition Policy Conference”. Washington, DC 1987
Food and Drug Administration Scientific Advisor 1985-1986 Provided advice and evaluated research data relative to attaining Public Health Service Objectives for Improved Nutrition in 1990.
Life Science Research Organization Scientific Expert 1981-1984 Evaluation and interpretation of data from National Nutrition and Health Examination Survey.

Books

Books Edited (Sole Editor)

  • Bailey LB. Folate in Health and Disease. 2nd Edition. Taylor and Frances. Boca Raton, FL ,2009, pgs 1-583.
  • Bailey LB. Folate in Health and Disease. Marcel Dekker, New York, NY, 1995, pgs 1-469.

Book Chapters Authored

  • Bailey, LB, da Silva, V, West, A, Caudill, M. Folate. In: Handbook of Vitamins, Taylor and Francis, 2013.
  • Bailey, LB, Caudill MA. Folate. In: Present Knowledge in Nutrition. International Institute of Life Sciences, 2012.
  • Kauwell, GPA, Diaz, M, Yang, Q, Bailey LB. Folate: Recommended intake consumption and status. In: Folate in Health and Disease, 2nd Ed., Bailey, L.B. (ed), Taylor Francis Press, Boca Raton, FL, pgs 467-490, 2009.
  • Falls BT and Bailey LB. Folate a key to optimal pregnancy outcome. In: Handbook of Nutrition and Pregnancy. Lammi-Keefe CJ and Couch SS (eds), Humana Press, Totowa NJ pgs 245-254, 2008.
  • Bailey LB. Folic Acid. In: Handbook of Vitamins. Zempleni J and Rucker R. (eds), CRC Press, Boca Raton, FL, 2007.
  • Bailey LB and Gregory JF. Folate. In: Present Knowledge in Health and Disease. 9th ed. Bowman B and Russel R. (eds), ILSI Press, Washington, DC, 2006.
  • Bailey LB and von Castel-Dunwoody K. Effect of inadequate B vitamin intake and extreme physical stress.  In: Optimization of Nutrient Composition of Military Rations for Short-Term, High-Stress Situations. IOM Committee on Military Nutrition, NAS Press, Washington, DC 2005. 
  • Bailey LB, Moyers S, Gregory JF Folate. In: Present Knowledge in Human Nutrition. 8th ed. Bowman B and Russell R. (eds), ILSI Press, 2001.
  • Bailey LB and Caudill MA. Pyridoxine. In: Parenteral Micronutrient Handbook. (Baumgartner TG, ed.)  (2nd edition) Fujisawa USA, Inc, 1997, pgs. 563-578.
  • Bailey LB and Caudill MA. Cyanocobalamin. In: Parenteral Micronutrient Handbook. Baumgartner, T G (ed.), (2nd edition), Fujisawa USA, Inc., 1997, pgs. 579-595.
  • Bailey LB and Caudill MA. Biotin. In: Parenteral Micronutrient Handbook. Baumgartner T G (ed.), (2nd edition), Fujisawa USA, Inc., 1997, pgs. 597-610.
  • Bailey, L B., and Caudill, M A. Folic acid. In: Parenteral Micronutrient Handbook. Baumgartner T G (ed.), (2nd edition), Fujisawa USA, Inc, 1997, pgs. 611-628.
  • Sitren HS, Bailey LB, Cerda JJ. Thiamin. In: Parenteral Micronutrient Handbook. Baumgartner TG (ed.), (2nd edition), Fujisawa USA, Inc, 1997, pgs. 483-498.
  • Sitren HS, Bailey LB, Cerda JJ. Riboflavin. In: Parenteral Micronutrient Handbook. Baumgartner TG (ed.), (2nd edition), Fujisawa USA, Inc, 1997, pgs. 499-514.
  • Bailey LB, Sitren HS, Cerda JJ.  Niacin. In: Parenteral Micronutrient Handbook. Baumgartner TG (ed.), (2nd edition), Fujisawa USA, Inc, 1997, pgs. 515-530.
  • Bailey LB, Sitren HS, Cerda JJ. Ascorbic Acid.  In: Parenteral Micronutrient Handbook. Baumgartner TG. (ed.), (2nd edition), Fujisawa USA, Inc, 1997, pgs. 531-548.
  • Bailey LB, Sitren HS, Cerda JJ. Pantothenic Acid.  In: Parenteral Micronutrient Handbook. Baumgartner TG. (ed.), (2nd edition), Fujisawa USA, Inc, 1997, pgs. 549-562.
  • Bailey LB.  Folate requirements and recommended dietary intakes.  In:  Folate in Health and Disease.  (Bailey LB, ed), Marcel Dekker, Inc, New York, 1995.
  • Bailey LB. Vitamin B6. In: Parenteral Micronutrient Handbook. Baumgartner T. (ed.), Lyphomed, Melrose Park, IL, 1991, pgs. 521-540.
  • Bailey LB. Folate. In: Parenteral Micronutrient Handbook. Baumgartner T. (ed), Lyphomed, Melrose Park, 1991, pgs. 573-590.
  • Bailey LB. Biotin. In: Parenteral Micronutrient Handbook. Baumgartner T. (ed), Lyphomed, Melrose Park, 1991, pgs. 559-572.
  • Bailey LB. Cyanocobalamin (Vitamin B12). In: Parenteral Micronutrient Handbook. Baumgartner T. (ed.) Lyphomed, Melrose Park, 1991, pgs. 451-468.
  • Sitren HS, Bailey LB, Cerda JJ. Riboflavin. In: Parenteral Micronutrient Handbook. Baumgartner T. (ed.) Lyphomed, Melrose Park, 1991, pgs. 451-468.
  • Sitren HS, Bailey LB, Cerda JJ. Thiamin. In: Parenteral Micronutrient Handbook. Baumgartner T. (ed.) Lyphomed, Melrose Park, 1991, pgs. 431-450.
  • Sitren HS, Bailey LB, Cerda JJ. Niacin. In: Parenteral Micronutrient Handbook. Baumgartner T. (ed.) Lyphomed, Melrose Park, 1991, pgs. 469-486.
  • Sitren H S, Bailey, L B, Cerda JJ. Ascorbic Acid.  In: Parenteral Micronutrient Handbook. Baumgartner, T. (ed.) Lyphomed, Melrose Park, 1991, pgs. 487-506.
  • Sitren HS, Bailey LB, Cerda JJ. Pantothenic acid. In: Parenteral Micronutrient Handbook. Baumgartner T. (ed.) Lyphomed, Melrose Park, 1991, pgs. 451-468.
  • Bailey LB. Vitamin and amino acid additives. In: Nutrient Additions to Food. Bauernfeind, JC (ed.) Wavely Press, Mellroe Park, IL, 1991, 109-142.
  • Bailey L B. Folate nutrition in adolescents and adults. In: Folic Acid Metabolism in Health and Disease. Picciano MF. Stokstad ELR, Gregory JF. (eds.), Wiley-Liss, New York, 1990, pgs. 253-276.
  • Bailey LB. Folate nutrition in adolescents and adults. In:  Folic Acid Metabolism in Health and Disease. Picciano MF, Stokstad ELR., Gregory JF. (eds). Wiley-Liss, New York, 1990.
  • Bailey LB. Iron and folate nutriture during life cycle. In: Aspects of Nutritional Physiology, Bourne, G. H. (editor), Karger, Basel, 1988, pgs. 56-86.
  • Bailey LB. Nutritional anemia. In: Nutritional Aspects of Aging. Chen L. (ed.), CRC Press. Cleveland Ohio, 1986, pgs. 207-229.